摘要
简单 Cu (OAc ) 联合协议的 2 催化 Sonogashira 被介绍。有终端炔属羟的许多芳基卤的政变石楠顺利被进行负担得起相应需要的产品在,这被发现对优秀收益中等,用 Cu (OAc ) 2 作为催化剂和 Et3N 作为溶剂。
A simple Cu(OAc)2 catalyzed Sonogashira coupling protocol is presented. It was found that the couplings of a variety of aryl halides with terminal alkynes were conducted smoothly to afford the corresponding desired products in moderate to excellent yields, using Cu(OAc)2 as the catalyst and Et3N as the solvent.