良恶性胃溃疡旁粘膜肠化生的观察

Study on intestinal metaplasia in the adjacent mucosa of the benign and malignant gastric ulcer

采用粘液组织化学染色方法，对５４例胃良恶性溃疡旁粘膜肠化生进行观察，发现胃癌癌旁粘膜不完全性结肠型肠化生的检出率明显高于胃溃疡病组。不完全性结肠型肠化生在组织学上有经异型增生向胃癌过渡的形态学特征，表示与胃癌关系密切，应视为癌前病变。提示临床对不完全性结肠型肠化生病例应追踪随访与复查，可及时发现早期胃癌。

Using mucin histochemical staining on the area of intestinal metaplasia(IM),54 specimen of the adjacent mucosa of the benign and malignant gastric ulcers were studied.The results showed that the detectable rate of IMof incomplete colonic type in gastric carcinoma was obviously higher than that in gastric ulcer(P<0.005).Histologically incomplete colonic type likely showed the transferring feature of epithelial dysplasia to gastric careinoma.