pH指示剂吸光度比值法测定枸橼酸钾溶液中枸橼酸钾含量

Quartitatire determination of kalii citratis in l00 g/L liquor kalii citratis by pH-indicator abosor-bance radio method

目的：测定１００ｇ／Ｌ构橼酸钾溶液的含量。方法：采用ｐＨ指示剂吸光度比值法，以０．５／Ｌ麝香草酚蓝醇溶液为指示剂，０．５ｍｏ１／Ｌ盐醚为标准液，测定波长为４３５ｎｍ和５５１ｎｍ。结果：线性关系良好，ｒ＝０．９９９８（ｎ＝５），平均回收率为９９．０２％（ｎ＝５），ＲＳＤ＝０．８７％。经与中和法比较，表明其测定结果与本法无显著性差异（Ｐ＞０．０５）。结论：本法准确度高，简便，快速，适用于医院制剂分析。

OBJECTIVE :To make an assay,a pH-indicator absorbance radio method was established for l00 g/LLiquor Kalii citrtis,METHOD:A pH-indicator absorbance radio method was used,0.5/L solution of thymol bluewas used as indicator and 0.5 mol/L hydrochloric acid solution as volumetric solution.The absorbance was mea-sured at 435 nm and 551 nm.RESULTs:The calobration curve was linear(r=0.999 8,n=5).The average recoveryfor the assay was 99. 02 with relative standard deviation of 0.87%(n=5).The resuIts obtained by using pH-indica-tor absorbance radio method and neutralization method respectively were not statistically significant(P> 0.05)CONCLUSION:The method is simple,rapid and suitable for analysis in hospital.