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基因芯片在药物靶标研究中的应用 被引量：1

Application of DNA microarray to drug targets study
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摘要 DNA芯片技术现已广泛应用于分子生物学、运用生物学以及临床医学等领域进行DNA鉴定、定量及功能分析。本文对基因表达谱芯片技术在阿尔茨海默病、帕金森病及恶性肿瘤相关药物靶点的发现、发展等方面的进展作一综述。 Assay systems based on DNA microarray technology are currently used for the identification, quantitation and functional analysis of DNA involved in molecule research, applied biology and diagnostic applications. In this paper, application of DNA microarray technology in the discovery, development and subsequent use of new therapeutic and drug targets in Alzheimer＇s disease, Parkinson＇s disease and malignancy are reviewed.
作者 黄璜 程肖蕊 周文霞 张永祥
机构地区 军事医学科学院毒物药物研究所
出处 《军事医学科学院院刊》 CSCD 北大核心 2006年第6期583-587,共5页 Bulletin of the Academy of Military Medical Sciences
基金 国家重点基础研究发展规划("973"计划)资助项目(2004CB518907) 国家自然科学基金资助项目(30200367 30600760)
关键词 基因芯片 药物靶标 阿尔茨海默病 帕金森病 恶性肿瘤 DNA microarray drug targets Alzheimer＇s disease Parkinson＇s disease malignancy
分类号 Q789 [生物学—分子生物学]
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同被引文献23

  • 1滕兰菊,桂芳,黄刚,李秀平.公丁香等17种中草药对肠道杆菌的体外抑菌实验[J].中医药临床杂志,2004,16(5):455-456. 被引量：9
  • 2徐仿周,吴继洲.基因芯片技术在中药中的应用研究进展[J].国外医学（药学分册）,2005,32(5):300-303. 被引量：10
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军事医学科学院院刊
2006年 第6期

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