散瘀化浊汤治疗非酒精性脂肪肝临床研究

The Clinical Study of Therapy Patients with Non-alcoholic Liver of Fat with Sanyuhuzhuo Decoction

目的：探讨中药制剂散瘀化浊汤对非酒精性脂肪肝的治疗作用与机制。方法：散瘀化浊汤治疗非酒精性脂肪肝患者60例，另设对照组60例，治疗前后观察患者体重、影像学变化，检测肝功与血脂（TG、TC、HDL、LDL）。结果：两组总有效率分别为93．3％、53．3％，治疗组肝功明显改善，血脂含量下降，肥胖者体重得到有效控制与减轻，声像图也显示肝脏质地的改善，与对照组比较均有显著差异（P〈0．05～0．001）。结论：散瘀化浊汤对脂肪肝具有良好的治疗效果，能够改善肝功、控制体重，降低血脂。

Objection： To study the clinical effect of Sanyuhuazhuo decoction in treating the patients with Non-alcoholic liver of fat. Methods： 60 patients were treated with Sanyuhuazhuo decoction in treatment group, and other 60 patients were treated with Essentiale Forte N, in two groups the changes of symptoms, systems and images were observed, liver faction and fat of blood were ex- amined before and after treatment. Results. The total effect ratio were 93.3% and 53.3% respectively in two groups, in treatment group the liver function of the patients were ameliorated distinctly and fat of blood descend, the avoirdupois of obesity patients were control effectively, the texture of liver were ameliorated distinctly by B ultrasonic, there are distinct difference in two groups（ P 〈 0. 05 -0. 0015）. Conclusion： The clinical observation indicated that Sanyuhuazhuo decoction has perfect curative effect in Non-alcoholic liver of fat, it can ameliorate the symptom, sign, liver function, fat of blood and control avoirdupois of obesity patients and then reduce the trauma of liver.