用乘子法同时测定复方替硝唑含漱液中二组分的含量(英文)

Simultaneous Determination of two Components in Compound Tinidazole Gargles by Multiply Factor Method

用乘子法处理多波长吸光度数据,同时测定复方替硝唑含漱液中二组分的含量。简要介绍了乘子法的原理和计算步骤,模拟样品中醋酸氯已定、替硝唑的平均回收率分别为99.75%,100.17%,标准偏差分别为0.73%,0.42%(n=10),对三个批号实际样品的测定结果与标准方法吻合。与标准方法相比,该方法具有简便、快速、易于实现自动分析的优点。

In this paper, the basic principle and computing of multiply factor method applied to multicomponent analysis were discussed. The method was applied to simultaneous determination of two components in compound tinidazole gargles. The average recovery of Chlorhexidine and tinidazole in simulation samples was 99.75%, 100. 17 and relative standard deviations for them were 0.73 %, 0. 42 % respectively （n= 10）. The results of determination for three batches of actual samples were agreed with those by standard method. This method promises well to be adopted as an official assay method for compound tinidazole gargles.