120例冠心病患者血清中肺炎衣原体特异性抗体的检测
摘要
目的研究肺炎衣原体（CP）感染与冠心病（CHD）的关系。方法应用酶联免疫法检测CHD组患者及健康对照组人群血清的CP特异性抗体IgG，同时应用全自动生化分析仪测定血清总胆固醇（TC）、甘油三酯（TG）、载脂蛋白A（ApoA）、载脂蛋白B（ApoB）、高密度脂蛋白（HDL—C）的浓度。结果CHD组CP阳性率为60％。对照组为30％，2组相比有显著性差异（P〈0．01）。CP阳性的CHD患者血清TC、TG浓度高于CP阴性患者，HDL—C浓度低于CP阴性患者。结论CHD患者血清中CP感染率较高，CP感染可能是影响CHD发生、发展的一个因素。
出处
《卫生职业教育》
2007年第2期126-127,共2页
HEALTH VOCATIONAL EDUCATION
参考文献4
-
1Saikku P,Leinonen M,Maila K,et al.Serological evidence of an association of a novel Chlamydia TWAR with chronic caronic coronary heart disease and acute myocardial infarction[J].Lance,1988,29(8618):983 ～986.
-
2Jackson LA,Campbell Schmid RA.Specifity of detection Chlamydia pneumoniae in cardiovascular atheroma[J].Am J Pathl,1997,150(5):1785～ 1890.
-
3Mass M,Krause E,Kruger S,et al.Coronary arteries harbour viable Chlamydia pneumoniae.Fourth international symposium on moden concepts in endocarditis and cardiovascular infections abstract[M].Yuerdon Les Baines:BainsSwitzerland,1997.101.
-
4卢敏.肺炎衣原体感染与冠心病[J].国外医学（老年医学分册）,2000,21(4):177-180. 被引量：4
二级参考文献16
-
1Kuvin JT, Kimmelstiel CD. Infectiou causes of atherosclerosis. Am Heart J,1999;37:216～226
-
2Aldous MB, Grayston JT, Wang SP et al. Seroepidemiology of chlamydia pneumoniae TWAR Infection in seattle families,1966-1979. J Infect Dis, 1992:166:.646～649
-
3Moazed T, Kuo CC, Patton DC et al. Experimental rabbit models of ehlamydia pneumoniae infection. Am J Pathol,1996;148:667～676
-
4Kuo C, Shor A, Campbell LA et al. Demonstration of chlamydia pneumoniae in atherosclerotic lesions of coronary arteriesJ Infect Dis,1993;167:841～849
-
5Gaydos CA, Quinn TC, Eiden TJ. Indentification of chlconydia pneumoniae By DNA amplifition of the 16s rRNA gene. J Clin microbiol. 1992;30:796～800
-
6Kuo CC, Grayston JT, Campbell LA et al. Chlamydia pneunoniae (TWAR) in coronary arteries of young adults (15～34 years old). Pro Natl Acad Sci,1995;92:6911～6914
-
7Libby P. Molecular bases of the acute coronary syndromes,Circulation, 1995;91:2844～2850
-
8Toss H, Gnarpe J, Gnarpe H et al. Increased fibrinogen levels are associated with persistent chlamydia pneumoniae infection in unstable coronary artery disease. Eur Heart J, 1998;19:570～557
-
9Shah PK, Falk E, Badimon TJ. Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques-potential role of matrix degrading metalloproteinases and implications for plaque rupture, Circulation,1995;92:1565～1569
-
10Gaydos CA, Summersgill JT, Sahney NN et al. Replication of chlamydia pneumoniae in vitro in human macrophages, endothelial cells, and aortic artery smooth muscle cells. Iafect Immun 1996;64:1614～1620
共引文献3
-
1赵春华,张静音,李娜,张培因,刘卓明.肺炎衣原体感染与冠心病相互关系的研究[J].标记免疫分析与临床,2005,12(2):70-72. 被引量：1
-
2张静音,王斌,张培因.肺炎衣原体感染与冠心病的相关性初探[J].中国综合临床,2004,20(2):104-105.
-
3王瑛,张静音,付强,杨国慧,赵艳,于旭.肺炎衣原体感染与老年人不稳定性心绞痛相关性的探讨[J].中华老年心脑血管病杂志,2004,6(2):87-89.
-
1高萍,田灵遵.呼伦贝尔市卫校教职工血清总胆固醇、甘油三酯检测及分析[J].卫生职业教育,2005,23(5):84-84.
-
2林建春.物理教学中“学困生”的转化重在激发学习兴趣的培养[J].新一代（理论版）,2011(9):99-99.
-
3吴琼,易图明.家兔载脂蛋白AⅠ和血脂与动脉壁脂质斑块及肝脂肪变的关系[J].卫生职业教育,2007,25(5):112-113.
-
4周媛媛,李超彦.黄精多糖对12月龄自然更年期大鼠血脂及血清SOD、MDA影响的实验研究[J].卫生职业教育,2012,30(22):88-89. 被引量：6
-
5康照昌,李玉荣.生姜透皮帖对动脉粥样硬化家兔血脂及内皮细胞功能的影响[J].卫生职业教育,2015,33(2):102-103. 被引量：4
-
6血脂并非越低越好[J].科技与生活,2011(8):61-61.
-
7白洲霞,杨建英.病毒性心肌炎巨细胞病毒特异性抗体和细胞免疫检测的意义[J].卫生职业教育,2006,24(14):92-93.
-
8张其连.某高校职工体检血脂分析[J].中国校医,2011,25(6):470-471. 被引量：1
-
9张艳平,刘录山,丁矢.肺炎衣原体的培养及对RAW264.7细胞的感染[J].卫生职业教育,2007,25(3):111-112.
-
10刘燕颖.重视学生甲、乙肝疫苗的接种工作[J].哈尔滨学院学报,1998,20(1):212-212.
