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Toll样受体与肾脏疾病 被引量：2

Toll-like receptors and kidney diseases
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摘要 Toll样受体(Tolllikereceptors,TLRs)作为一类病原模式识别受体在免疫应答和炎症反应中发挥重要作用。新近研究表明,TLRs家族的成员可能参与介导炎症性肾脏病和泌尿系统感染性疾病的发生。现就TLRs的生物学特征及其与肾脏疾病的关系等方面予以综述。 Toll-like receptors （TLRs）, a family of pathogen recognition receptors, play an important role in immune responses and inflammation. It has been recently demonstrated that members of the TLR family are involved in immune-mediated renal diseases and urinary tract infections. The biological characteristics of TLRs and their roles in the pathogenesis of kidney diseases were discussed in this review.
作者 张瑜 周建华
机构地区 华中科技大学同济医学院附属同济医院儿科
出处 《临床儿科杂志》 CAS CSCD 北大核心 2007年第1期71-73,共3页 Journal of Clinical Pediatrics
关键词 TOLL样受体 肾脏疾病 生物学特征 Toll-like receptors kidney diseases biological characteristica
分类号 R692 [医药卫生—泌尿科学]
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参考文献19

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同被引文献57

  • 1何展荣,杨利.小儿支原体肺炎并发肾脏损害40例临床分析[J].医学临床研究,2006,23(2):249-250. 被引量：2
  • 2闵亚丽,于黔,肖俊.冬虫夏草在肾间质纤维化大鼠模型中的作用及其对TGF-β_1、α-SMA的影响[J].中国中西医结合肾病杂志,2007,8(2):92-93. 被引量：42
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  • 8Srichai MB, Hao C, Davis L, et al. Apoptosis of the thick ascending limb results in acute kidney injury [J]. J Am Soc Nephrol, 2008,19(8) : 1538-1546.
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临床儿科杂志
2007年 第1期

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