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XRCC1基因在肿瘤研究中的应用 被引量：4

Application of XRCC1 gene in cancer research
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摘要 肿瘤是一种基因病,基因组的稳定与否和肿瘤的发生密切相关。XRCC1基因是一种DNA损伤修复基因,在基因组损伤后的修复过程中发挥作用,对维持基因组的稳定,预防肿瘤的发生有着重要的意义。本文就XRCC1基因的生物学特点,该基因单核苷酸多态性与肿瘤易感性,以及该基因的研究方法等方面进行了文献回顾,为该基因用于肿瘤的预防、诊治提供理论借鉴。 Cancer is one of the gene diseases. The genome stability is closely associated with the occurrence of cancers. XRCC1 gene is one of the DNA repair genes. It participates in the repair process when the genome is injured. So it is considered important in maintaining the stability of the genome and in the prevention of tumor occurrence. This article introduced the characteristic of XRCC1 gene, the relationship between single nucleotide polymorphism of the gene and susceptibility to tumor, and the common methods used in the XRCC1 research.
作者 傅锦业 吴毅
机构地区 复旦大学肿瘤医院头颈外科
出处 《中国癌症杂志》 CAS CSCD 2007年第1期92-94,共3页 China Oncology
关键词 XRCC1基因 肿瘤 XRCC1 gene neoplasm
分类号 R73-34 [医药卫生—肿瘤]
  • 相关文献

参考文献12

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共引文献55

同被引文献37

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引证文献4

二级引证文献9

中国癌症杂志
2007年 第1期

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