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生物素-链霉亲和素系统检测乙型肝炎患者T淋巴细胞亚群

THE DETECTION OF T LYMPHOCYTE SUBSETS IN VIRAL HEPATITIS B WITH BIOTIN-STREPTAVITIN SYSTEM
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摘要 应用生物素-链霉亲和素方法检测了乙型病毒性肝炎(HBV)患者外周血T淋巴细胞亚群。旨在探讨乙型病毒性肝炎患者的T淋巴细胞的功能,其结果为各患者的CD_6^+、CD_4^+、CD_3^+和CD_4^+/CD_4^+均明显高于正常人,其与正常人相比较,差别均有高度显著性(P<0.01)。表明乙型病毒性肝炎主要是杀伤性T淋巴细胞(T_c)参与了肝损害。 In order to study cellular immune function of patients with viral hepatitis B, peripheral blood T lymphocyte subsets were detected by biotin-str- eptavidin system. The results showed that CD2+, CD4+, CD6+ and CD4+/CD3+ were significantly higher than those in normal people ( P<0.01 ) . The results indicated that the liver was mainly damaged by cytotoxic T-cell (Tc)in patients with viral hepatitis B.
出处 《齐齐哈尔医学院学报》 1996年第4期245-247,共3页 Journal of Qiqihar Medical University
关键词 生物素 链霉亲和素 淋巴细胞亚群 乙型肝炎 Biotin-streptavidin Lymphocyte subsets Viral hepatitis B
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