社区与医院内感染菌株的分布比较及耐药性分析

Distribution of Pathogen in Commuity and Hospital and Its Drug Resistance

目的:为比较近期我院及社区感染性疾病的病原菌构成特点及了解其对抗生素耐药情况。方法:回顾性分析了2005年全年门诊及住院患者的细菌培养及药敏结果。结果:社区与住院患者的G-菌,排在前3位的均为大肠埃希菌、铜绿假单胞菌、肺炎克雷伯菌;G+菌,住院患者排在前3位的是屎肠球菌、表皮葡萄球菌、粪肠球菌;社区前3位则为表皮葡萄球菌、链球菌属、金黄色葡萄球菌。药敏结果显示,大肠埃希菌对环丙沙星、氧氟沙星、哌拉西林、复方新诺明的耐药率较高,铜绿假单胞菌对头孢类抗生素的耐药率要高于大肠埃希菌。结论:无论社区感染还是院内感染的患者一定要重视细菌培养,注重对病原菌及其耐药性的检测,用检测结果指导合理用药。

Objective. To compare the distribution of pathogenic bacteria of infectious diseases between in our hospital and in commuity, and to learn about its drug resistance. Methods-The results of bacteria culture and susceptibility test in clinic and hospital patients in 2005 were retrospectively analyzed. Results： The first three G^- fungus in community and hospital patients were sherichia coli, pseugomonas qeruginosa and klebsiella pneumoniae. The first three G^＋ fungus in hospital patients were enteroeoecus faeclum, staphylococcus epidermidis and enterococeus faeealis, those in community patients were staphylococcus epidermidis, streptococcus and staphylococcus auieus. The results of susceptibiility test showed esherichia coli resistance in eipprofloxacin, ofloxcin, piperacillin and sulfamethoxazole timethopim, pseugomonas aeruginosa resistance in eephalosporins.Conelusion： Bacteria culture showld be recommended in both commuity and hospital. The detection of pathogenic bacteria and its drug resistance is helpful for rational administration.