铅与X线复合作用对大鼠致畸效应的实验研究

TERATOGENIC EFFECTS OF LEAD AND X-RAYS IN COMBINATION ON THE RATS

本文报道了铅与Ｘ线（单独或复合）对大鼠的致畸效应，并与铅、Ｘ线的单独作用进行了比较。结果显示，复合作用对胚胎的致畸毒性有所减轻，但对胎鼠的损伤效应不一。死胎率和畸胎率均有所下降，而胎鼠的生长发育受到干扰。孕鼠的体重和胎鼠的骨骼畸形各组间无显著性差异。

This paper reports the teratogenic effects of lead and X-rays,aolne or in combination,on the rats.The comparison with the teratogenic effects of lead and X-rays alone has been done.The results indicate that there was a decrease in teratogenic embryotoxicity of the combined treatment than the single treatment,but the damage effects on the fetuses of the rats is inconsistent.Both the rate of dead fetuses and of the monstra were decreased but the development of the fetuses was disturbed.There was no significant difference among these groups in the body weight of the pregnant rats and the skeletal malformation of the fetuses.