摘要
本组对２３例手术、病理证实为原发性肝癌（ＰＨＣ）的ＭＲＩ影像学所见，与用图像分析仪测定的癌细胞核ＤＮＡ含量倍体均值（Ｕ值）进行相关性研究，并作统计学处理。结果表明：ＭＲＩ显示肿瘤稍低／高信号，瘤径≥５ｃｍ、瘤内坏死、边缘浸润等改变与ＤＮＡ含量明显相关。本文提示：通过对ＰＨＣ的ＭＲＩ信号及形态分析，可大致反映ＤＮＡ含量的高低，从而推测其生物学特性，对临床治疗及预后估计有重要价值。
The DNA ploidy content was carried out on the paraffin - embedded material from 23 cases who received hepatectomy for Primaly Hepatic Carcinoma (PHC) by using an image analyzer. MR Imaging of there 23 cases of PHC was studied correlatively with the nuclear DNA ploidy content. The results showed that there was singificent difference in the nuclear DNA content between:tumors with slightly hypointense signal on T1WI, slightly hyperintense on T2WI and those tumors with slightly htpointense signal on T1WI and highly hyperintense on T2WI (P<0. 001 );tumor diameter>5cm and those≤5cm (P<0. 05 ); tumors with necrosis and take without nerosis (P<0. 01 ); tumors with a distinct margin without localized bulging and the with infiltration (P<0. 001).conclusion: By correlative study, MRI signal and morphology can reflect the nuclear DNA content Of PHC and thereby have value in prediction of the biologic behaveal of PHC.
