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牙源性角化囊肿上皮组织中Bcl-2蛋白的表达 被引量：2

Expression of Bcl-2 protein in epithelial tissue of odontogenic keratocyst
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摘要 目的:观察牙源性角化囊肿(OKC)上皮组织中Bcl-2蛋白的表达,探讨其与OKC生长特性的关系。方法:采用免疫组织化学法检测10例OKC、10例含牙囊肿(DC)、10例单囊型成釉细胞瘤组织中Bcl-2蛋白的表达。结果:OKC中6例(60%)Bcl-2阳性着色,阳性着色位于基底层细胞。DC中1例(10%)Bcl-2阳性着色,UA中10例(100%)均呈Bcl-2阳性着色,3组间Bcl-2阳性表达率差异有统计学意义(P<0.05)。结论:OKC基底层细胞Bcl-2的阳性表达,可能与OKC上皮增殖及其侵袭性生长有关。 Aim ： To detect the expression of Bcl-2 protein in the epithelial tissue of odontogenie keratocysts （OKC）. Methods： The expression of Bcl-2 in OKC （n = 10）, dentigerous cyst （DC） （n = 10） and unicystic ameloblastoma （UA） （n = 10） tissue was detected using immunohistochemistry. Results： The positive expression rate of Bcl-2 was 60% in OKC 10% in DC, and 100% in UA. The positive rate of Bcl-2 expression was statistically different among the three groups （ P 〈 0.05 ）. Conclusion ： The positive expression of Bcl-2 in the basal cell layer of OKC may be related to the proliferation Qf OKC epithelium and its aggressive behavior.
作者 彭利伟 赵怡芳
机构地区 郑州大学口腔医学院口腔颌面外科 武汉大学口腔医学院口腔颌面外科
出处 《郑州大学学报（医学版）》 CAS 北大核心 2007年第1期92-93,共2页 Journal of Zhengzhou University(Medical Sciences)
关键词 牙源性角化囊肿 含牙囊肿 单囊型成釉细胞瘤 BCL-2 odontogenic keratocyst dentigerous cyst unicystic ameloblastoma Bcl-2
分类号 R782 [医药卫生—口腔医学]
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参考文献8

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同被引文献25

  • 1Myoung H, Hong S - P, Hong S - D, et al. Odontogenic keratocyst: Review of 256 cases for recurrence and clinicopathologic parameters [ J ]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2001, 91:328-333
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  • 5Kim DK, Ahn SG, Kim J, et al. Comparative Ki -67 expression and apoptosis in the odontogenic keratocyst associated with or without an impacted tooth in addition to unilocular and muhilocular varieties [J]. Yonsei Med J, 2003, 44:841 -846
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郑州大学学报（医学版）
2007年 第1期

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