长骨嗜酸性肉芽肿的影像诊断

Imaginal diagnosis of eosinophilic granuloma of long bones

目的分析长骨嗜酸性肉芽肿的临床与影像表现,提高对本病的诊断水平。方法回顾性分析经手术或穿刺病理证实的24例长骨嗜酸性肉芽肿的临床和影像学资料,所有病例均作X线平片检查,其中加作CT检查6例,MRI检查4例。结果24例中男15例,女9例,平均年龄14.7岁;22例单发,2例多发,发生于股骨14例,胫骨5例,肱骨3例,腓骨2例,其中发生于骨干16例,干骺端8例;主要表现为骨质破坏、邻近骨皮质改变、骨膜反应和软组织肿块/肿胀。结论长骨嗜酸性肉芽肿的影像表现有一定的特征性,综合分析能提高对该病的诊断水平。

Objective To analyze the clinical and imaging features of eosinophilic granuloma of long bones so as to improve diagnosis accuracy of the disease. Methods The clinic materials and imaging findings of 24 patients with eosinophilic granuloma of long bones proved by surgery or histopathology were analyzed retrospectively. All the patients received radiography; CT scan was performed in 6 cases; and MRI was done in 4 cases. Results Fifteen patients out of 24 were male and 9 were female, with the average age 14.7 years old. Solitary lesion was found in 22 cases, and multiple bone destruction was noted in 2 cases. There were 14 lesions located in femur; 5 in tibia; 3 in humer; and 2 in fibula. In total 16 lesions involved diaphysis and is 8 cases the metaphysis was invaded. Bone destruction, the changes of the adjacent cortex, periosteal reaction and soft tissue mass or swelling were demonstrated in images obtained. Conclusion The imaging features in eosinophilic granuloma oflong bones are characteristic. Careful and integrative analysis of imaging findings improves diagnosis accuracy of the disease.