急性白血病骨髓活检细胞中PTEN mRNA、hTERT和DNA-PKcs的表达及其意义
被引量：2
摘要
我们对PTEN mRNA、端粒酶逆转录酶（hTERT）和DNA蛋白激酶催化亚单位（DNA-PKcs）的表达进行检测，研究其在儿童白血病发生中的作用及其临床意义。
出处
《中华儿科杂志》
CAS
CSCD
北大核心
2007年第1期74-75,共2页
Chinese Journal of Pediatrics
基金
江苏省卫生厅重点临床专科资助基金项目(H200143)
参考文献4
-
1Ermoian RP, Furniss CS, Lamborn KR, et aL Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival. Clin Cancer Res, 2002,8: 1100-1106.
-
2Takeuchi S, Takeuchi N, Fermin AC, et al. Fmmeshift mutations in cnspnse-5 and other target genes in leukemia and lyphoma cell lines having microsatellite instability. Leukemia Res, 2003, 27 : 359-361.
-
3Kyo S, Kanaya T, Takakura M, et al. Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues. Int J Cancer, 1999, 80:60-63.
-
4Eriksson A, Lewensoh R, Larsson R, et al. DNA-dependent protein kinase in leukaemia cells and correlation with drug sensitivity. Anticancer Res, 2002,22 : 1787-1793.
同被引文献35
-
1Lirong Diao Ye-Guang Chen.PTEN,a general negative regulator of cyclin D expression[J].Cell Research,2007,17(4):291-292. 被引量：9
-
2娄超,黄高昇.霍奇金淋巴瘤R-S细胞PTEN基因的表达与意义[J].中华肿瘤防治杂志,2007,14(10):741-743. 被引量：1
-
3Hogarth LA, Hall AG. Increased BAX expression is associated with an increased risk of relapse in childhood acute lymphocytic leukemia. Blood, 1999,93(8) :2671-2678.
-
4Nera KP, Kohonen P, Narvi E, et al. Loss of Pax5 promotes plasma cell differentiation. Immunity, 2006,24 ( 3 ) : 283-293.
-
5Robichaud GA, Nardini M, Laflamme M, et al. Human Pax-5 C-tertninal isoforms possess distinct transactivation properties and are differentially modulated in normal and malignant B cells.J Biol Chem,2004,279(48) : 49956-49963.
-
6Tiacci E, Pileri S, Orleth A, et al. PAX5 expression in acute leukemias: higher B-lineage specificity than CD79a and selective association with t(8: 21 )-acute myelogenous leukemia. Cancer Res,2004,64(20):7399-7404.
-
7Valbuena JR, Medeiros LJ, Rassidakis GZ, et al. Expression of B cell-specific activator protein/PAX5 in acute myeloid leukemia with t(8; 21 ) (q22; q22) . Am J Clin Pathol, 2006,126(2) : 235-240.
-
8Zhang X, Lin Z, Kin I. Pax5 expression in non-Hodgkin' s lymphomas and leukemia. Korean Med Sci ,2003, 18(6) :804-808.
-
9Wenming C, Jiazhi Z,Shuzhen T,et al. Inactivation of p16 gene in leukemia. Chin Med Sci J, 1999,14(4) :206-210.
-
10Kees UR, Terry PA, Ford J, et al. Detection of hemizygous deletions in genomic DNA from leukaemia specimens for the diagnosis of patients. Res, 2005 ,29(2) : 165-171.
-
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-
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-
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-
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-
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