摘要
目的探讨^(125)Ⅰ粒子组织间永久置入在骨转移瘤中的治疗价值。方法对22例不同来源骨转移瘤患者采取^(125)Ⅰ粒子永久置入的方法进行治疗,观察治疗后骨痛缓解及术后病灶影像改变的情况。结果 ^(125)Ⅰ粒子永久置入治疗骨转移瘤止痛有效率为91%(20/22),术后2个月粒子置入病灶的影像检查结果显示,32个骨转移灶中,完全缓解(CR)4个、部分缓解(PR)18个、稳定(NC)10个,总缓解率68.7%,所有患者均未出现严重不良反应。结论组织间永久置入^(124)I 粒子治疗骨转移瘤止痛效果好,不良反应发生率低且程度轻,是一种疗效较好的治疗方法。
Objective To evaluate the value of ^125I permanent plantation in treating osseous metastases. Methods Twenty-two patients with osseous metastases were accepted radioactive seeds ^125I permanent plantation. The curative effect was appraised according to the degree of ostalgia relieving and the changing of the radiology imaging in patients. Results Accepted radioactive seeds ^125I permanent plantation, relief of pain was obtained and the effective rate is 91% （20/22）. However none of the patients showed severe side-effect. Among 32 lesions in 22 cases followed-up by CT in 2 months, 4 obtained CR, 18 obtained PR, 10 NC and 0 PD. The responsive rate was 68.7%. Conclusion ^125I permanent plantation procedure can be a safe and effective method in treating osseous metastases and obtaining good clinical effects with minimal damage and few complications.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2007年第1期76-78,共3页
Chinese Journal of Radiology
