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青藤碱贴剂透皮吸收数据的灰色GM(1,1)拟合及与相关模型的比较研究 被引量:1

The transdermal absorption data' GM(1,1) fitting of sinomenine liposome patch and comparison with related model
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摘要 目的:对青藤碱贴剂的透皮吸收数据进行灰色GM(1,1)模型拟合并与相关模型进行比较。方法:采用Franz扩散池进行体外透皮实验,通过累加生成建立透皮吸收数据的灰色GM(1,1)模型。结果:以平均相对偏差和灰色绝对关联度为评价标准进行拟合精度的比较。结论:灰色GM(1,1)模型的拟合精度较高。 AIM : The transdermal absorption data of sinomenine patch was fitted by grey model GM ( 1,1 ) and compared with other models. METHODS: The transdermal absorption experiment was carried out with Franz diffusion cell and the GM( 1,1 ) was established by accumulation generation operator (AGO). RESULTS: The fitting precision was compared by using mean relative error and grey absolute correlation degree as evaluation criterion. CONCLUSION : The fitting precision of GM ( 1,1 ) is as high as acceptable.
机构地区 广州中医药大学
出处 《中成药》 CAS CSCD 北大核心 2007年第1期48-51,共4页 Chinese Traditional Patent Medicine
基金 国家自然科学基金(编号3037178330672669) 广东省自然基金项目(编号31473)
关键词 青藤碱贴剂 透皮吸收数据 灰色GM(1 1)拟合 精度比较 sinomenine patch transdermal absorption data GM ( 1,1 ) fitting precision comparison
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