摘要
目的:对青藤碱贴剂的透皮吸收数据进行灰色GM(1,1)模型拟合并与相关模型进行比较。方法:采用Franz扩散池进行体外透皮实验,通过累加生成建立透皮吸收数据的灰色GM(1,1)模型。结果:以平均相对偏差和灰色绝对关联度为评价标准进行拟合精度的比较。结论:灰色GM(1,1)模型的拟合精度较高。
AIM : The transdermal absorption data of sinomenine patch was fitted by grey model GM ( 1,1 ) and compared with other models. METHODS: The transdermal absorption experiment was carried out with Franz diffusion cell and the GM( 1,1 ) was established by accumulation generation operator (AGO). RESULTS: The fitting precision was compared by using mean relative error and grey absolute correlation degree as evaluation criterion. CONCLUSION : The fitting precision of GM ( 1,1 ) is as high as acceptable.
出处
《中成药》
CAS
CSCD
北大核心
2007年第1期48-51,共4页
Chinese Traditional Patent Medicine
基金
国家自然科学基金(编号3037178330672669)
广东省自然基金项目(编号31473)