摘要
目的为了了解长春地区儿童甲型肝炎自然感染情况。方法采用竞争性抑制ELISA法检测甲型肝炎抗体。结果对417名儿童进行甲肝抗体检测,甲肝病毒抗体-IgG阳性176例,自然感染率为42.21%,学龄前儿童与学龄后儿童自然感染率分别为36.47%和63.64%,统计学分析差异显著,表明甲型肝炎的自然感染率学龄后儿童甲型肝炎的易感率较高。结论0-6岁儿童抗体水平较低,随着年龄的增长,甲肝抗体阳性率呈现上升趋势。
Objective: To study the natural infectious rate of viral hepatitis A in children of Changchun area. Methods: Adopting competitive inhibition Enzyme - linked immunoadsordent assay (ELISA) , we detected the antibody to hepatitis A in serum. Results: In 417 children, the positive rate of antibody to hepatitis A - IgG is 42. 21% (176/417), the natural infectious rate of children preschool age and school age are 36. 47% and 63.64%, respectively. There are the significant difference between children preschool age and school age. The susceptible rate of the natural infectious of viral hepatitis A in school age is higher than others. Conclusions : The level of antibody to hepatitis A in serum is lower between 0 and 6 ages. With the age increasing, the positive rate of IgG of:antibody to hepatitis A show a rising tendency.
出处
《中国优生与遗传杂志》
2007年第1期106-107,共2页
Chinese Journal of Birth Health & Heredity