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Correlation Factor Analysis of Retinal Microvascular Changes in Patients With Essential Hypertension

Correlation Factor Analysis of Retinal Microvascular Changes in Patients With Essential Hypertension
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摘要 Objectives To investigate correlation between retinal microvascular signs and essential hypertension classification. Methods The retinal microvascular signs in patients with essential hypertension were assessed with the indirect biomicroscopy lens, the direct and the indirect ophthalmoscopes were used to determine the hypertensive retinopathy grades and retinal arteriosclerosis grades. The rank correlation analysis was used to analysis the correlation these grades with the risk factors concerned with hypertension. Results Of 72 cases with essential hypertension, 28 cases complicated with coronary disease, 20 cases diabetes, 41 cases stroke, 17 cases renal malfunction. Varying extent retinal arterioscleroses were found in 71 cases, 1 case with retinal hemorrhage, 2 cases with retina edema, 4 cases with retinal hard exudation, 5 cases with retinal hemorrhage complicated by hard exudation, 2 cases with retinal hemorrhage complicated by hard exudation and cotton wool spot, 1 case with retinal hemorrhage complicated by hard exudation and microaneurysms, 1 case with retinal edema and hard exudation, 1 case with retinal microaneurysms, 1 case with branch retinal vein occlusion. The rank correlation analysis showed that either hypertensive retinopathy grades or retinal arteriosclerosis grades were correlated with risk factor lamination of hypertension (r=0.25 or 0.31, P 〈0.05), other correlation factors included age and blood high density lipoprotein concerned about hypertensive retinopathy grades or retinal arteriosclerosis grades, but other parameters, namely systolic or diastolic pressure, total cholesterol, triglyceride, low density lipoprotein cholesterol, fasting blood glucose, blood urea nitrogen and blood creatinine were not confirmed in this correlation analysis (P 〉 0.05). Conclusions Either hypertensive retinopathy grade or retinal arteriosclerosis grade is close with the hypertension risk factor lamination, suggesting that the fundus examination of patients with hypertension plays a important part in predicting the incidence of cardiovascular events. Objectives To investigate correlation between retinal microvascular signs and essential hypertension classification. Methods The retinal microvascular signs in patients with essential hypertension were assessed with the indirect biomicroscopy lens, the direct and the indirect ophthalmoscopes were used to determine the hypertensive retinopathy grades and retinal arteriosclerosis grades. The rank correlation analysis was used to analysis the correlation these grades with the risk factors concerned with hypertension. Results Of 72 cases with essential hypertension, 28 cases complicated with coronary disease, 20 cases diabetes, 41 cases stroke, 17 cases renal malfunction. Varying extent retinal arterioscleroses were found in 71 cases, 1 case with retinal hemorrhage, 2 cases with retina edema, 4 cases with retinal hard exudation, 5 cases with retinal hemorrhage complicated by hard exudation, 2 cases with retinal hemorrhage complicated by hard exudation and cotton wool spot, 1 case with retinal hemorrhage complicated by hard exudation and microaneurysms, 1 case with retinal edema and hard exudation, 1 case with retinal microaneurysms, 1 case with branch retinal vein occlusion. The rank correlation analysis showed that either hypertensive retinopathy grades or retinal arteriosclerosis grades were correlated with risk factor lamination of hypertension (r=0.25 or 0.31, P 〈0.05), other correlation factors included age and blood high density lipoprotein concerned about hypertensive retinopathy grades or retinal arteriosclerosis grades, but other parameters, namely systolic or diastolic pressure, total cholesterol, triglyceride, low density lipoprotein cholesterol, fasting blood glucose, blood urea nitrogen and blood creatinine were not confirmed in this correlation analysis (P 〉 0.05). Conclusions Either hypertensive retinopathy grade or retinal arteriosclerosis grade is close with the hypertension risk factor lamination, suggesting that the fundus examination of patients with hypertension plays a important part in predicting the incidence of cardiovascular events.
出处 《South China Journal of Cardiology》 CAS 2006年第2期114-118,92,共6页 岭南心血管病杂志(英文版)
关键词 Essential hypertension Ophthalmoscopy Retinal arteriosclerosis Correlation analysisBlood pressure Essential hypertension Ophthalmoscopy Retinal arteriosclerosis Correlation analysisBlood pressure
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参考文献10

  • 1The New Zealand Guidelines Group.The assessment andmanagement of cardiovascular risk[M/OL]. New Zealand:2003. http: / /www.nzgg. org.nz/library/gl_complete/ bloodpressure /index.cfm#contents . 2003
  • 2Cuspidi C,Meani S,Salerno M, et al.Retinalmicrovascular changes and target organ damage inuntreated essential hypertensives[].Journal of Hypertension.2004
  • 3Wong TY,Hubbard LD,Klein R, et al.Retinalmicrovascular abnormalities and blood pressure in olderpeople: the Cardiovascular Health Study[].British Journal of Ophthalmology.2002
  • 4Michael D.Ocular disorders associated with systemicdiseases[].Dayniel Vaughan General Ophthalmo-logy.1999
  • 5Fodor GJ,Frohlich JJ,Genest JJ Jr, et al.Recom-mendations for the management and treatment ofdyslipidemia[].Canadian Medical Association Journal.2000
  • 6Guidelines Subcommittee.Guidelines Subcommittee 1999World Health Organization-International Society of Hyper-tension Guidelines for the Management of Hypertension[].Journal of Hypertension.1999
  • 7Patton N,Aslam T,Macgillivray T, et al.Retinalvascular image analysis as a potential screening tool forcerebrovascular disease: a rationale based on homologybetween cerebral and retinal microvasculatures[].Journal of Anatomy.2005
  • 8Wong TY,Knudtson MD,Klein R, et al.A prospectivecohort study of retinal arteriolar narrowing and mortality[].American Journal of Epidemiology.2004
  • 9Wong TY.Is retinal photography useful in the measure-ment of stroke risk[].The Lancet Neurology.2004
  • 10Wong TY,,Mcintosh R.Systemic associations of retinalmicrovascular signs: a review of recent population-basedstudies[].Ophthalmic and Physiological Optics.2005

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