卵巢非霍奇金淋巴瘤11例临床分析

Clinical analysis of the eleven cases with ovarian non-Hodgkin's lymphoma

目的：探讨卵巢非霍奇金淋巴瘤（NHL）的诊断、治疗及预后。方法：从1995年10月-2005年8月对11例卵巢NHL进行手术、化疗及放疗。化疗采用CHOP、mBACOD、MACOP及PROMACE-CYtaBOM方案，3例行骨髓移植，接受超大剂量化疗。结果：1例术后拒绝化疗，出院后失访；1例骨髓移植，接受超大剂量的化疗后12月无复发；9例随访至死亡。最短生存5月，最长生存26月，中位生存13月。结论：卵巢NHL预后差，应采取综合治疗。

Objective：To explore the diagnosis, treatment and prognosis of the Ovarian Non-Hodgkin＇s Lymphoma （NHL）. Methods：From October 1995 to August 2005, 11 Patients had received therapy as surgery, radiotherapy and chemotherapy. Regimens of chemotherapy with CHOP, mBACOD, MACOP as well as ProMACE-CytaBOM and so on. 3 Patients was had gotten super high dose chemotherapy after bone marrow transplantation. Results：One patient was refused to receive chemotherapy and miss following up after operation, The other obtained 12 months diseases free survival when was given super high dose chemotherapy; 9 patients had been followed up till death, The median survival time was 13 months （range 5 -26 months）. Conclusion：The prognosis of Ovarian NHL is very zrievous. The combined modality therapy should be taken.