期刊文献+

卡维地洛治疗慢性充血性心力衰竭的临床疗效观察

下载PDF
导出
摘要 目的观察卡雏地洛治疗慢性充血性心力衰竭(chronic hear failure,CHF)的临床疗效。方法选择我院68例慢性充血性心力衰竭患者随机分为治疗组、对照组各34例。对照组使用洋地黄、利尿剂、血管紧张素转换酶抑制剂、硝酸酯类等药物治疗,治疗组在常规治疗的基础上,加用卡雏地洛,起始剂量2.5mg/次,1次/d,每周剂量加倍,遥渐增量至10~20mg/d,疗程6个月。每周测量血压、心率、评定心功能,治疗前、后检查超声心动图。结果两组患者临床疗效、病死率间差异均无显著性意义(P〉0.05)。但治疗组左室射血分数(LVEF)、左室舒张末期内径(LVEDD)和收缩末期内径(LVESD)均较对照组明显改善(P〈0.05)。结论卡维地洛治疗慢性充血性心力衰竭能改善心功能,改善左室重塑。
出处 《实用心脑肺血管病杂志》 2006年第11期891-892,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
  • 相关文献

参考文献5

二级参考文献17

  • 1CIBIS- Ⅱ Investigators and committees. The Cardiac Insufficiency Bisoprolol Study2 (CIBIS) : A randomized trial [J] . Lancet, 1999, 353(1946) : 9 - 13.
  • 2Barr CS, Abdelwahab N, Freeman M, et al. QT dispersion and sudden unexpected death in chronic heart failure [J] .Lancet, 1994; 343(8893) : 327 - 329.
  • 3Eichhron E J, Bristow MR. Medical therapy can improve the biologic properties of the chronically failing heart : A new era in the treatment of the heart failure [J] . Circulation, 1996, 94 (9) : 2285 -2296.
  • 4Metra M, Nodari S, Parrlnello G, et aL Marked improvement in left ventricular ejection fraction during long term β - blockade in patients with chronic heart failure: Clinical correlates and prognostic significance[J] . Am heart J, 2003, 145 (2) : 292 -299.
  • 5Brendrop B, Elming H, Jun L, et al. QT dispersion has no prognostic information for patients with advanced congestive heart failure and reduced left ventricular systolic function [ J] . Circulation, 2001, 103(6) : 831 -835.
  • 6Yoshimura M, Yasue H, Okumura K, et al. Different secretion patterns of atrial natriuretic peptide and brain natriuretic peptide in patients with congestive heart failure[J]. Circulation,1993,87(2):464-469.
  • 7Levin ER, Gardnetr DG, Samson WK. Natriuretic peptides[J]. N Engl J Med,1998,399:321-328.
  • 8Kruger S, Graf J, Kunz D, et al. Brain natriuretic peptide levels predict functional capacity in patients with chronic heart failure[J]. J Am Coll Cardiol,2002,40:718-722.
  • 9Maeda K, Takayoshi T, Wada A, et al. Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction[J]. Am Heart J,1998,135:825-832.
  • 10Hobbs RE. Using BNP to diagnose,manage,and treat failure[J]. Cleve Clin J Med,2003,70(4):333-336.

共引文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部