Angioseal血管闭合器在冠脉介入术后患者股动脉穿刺部位的应用

Use of Angioseal arterial puncture closing devices in patients after cardiac catheterization

目的评价冠脉介入术后应用Angioseal血管闭合器封堵股动脉穿刺部位的安全性、可行性及临床实用性。方法87例接受冠状动脉支架植入术的冠心病患者随机分为血管闭合器组(41例)和对照组(46例),分别采用Angioseal血管闭合器和传统徒手压迫方法止血。术后通过临床表现及血管彩色多普勒检查评估血管闭合器用于封堵股动脉穿刺部位的安全性、可行性及临床实用性。结果2组间止血成功率无明显统计学意义(97.6%vs 100%,P>0.05),血管并发症发生率无明显统计学意义(P>0.05),但血管闭合器组平均止血时间较对照组明显缩短(P<0.001),术后制动时间明显缩短(P<0.001)。结论Angioseal血管闭合器用于临床封堵股动脉穿刺部位安全、可靠,有一定的临床实用性。

Objective To assess the safety and efficacy of Angioseal arterial puncture closing devices, compared with standard manual compression in patients undergoing coronory angiograpby and percutaneous vascular interventions.Methods Eighty - seven patients undergoing coronory angiography and percutancous vascular interventions were randomly divided into control group（ n = 46） and Angioseal group（ n = 41）. The safety and efficaty of the arterial puncture closing deviee（Angioseal） was evaluated by clinical manifestations and vascular color Doppler uhrasonography. Results The mean time of hemostasis was significantly shorter（ P 〈 0.001 ） in the Angioseal group （54 ± 18 seconds） than in the control group （22 ± 6.5 minutes）. Time of immobilization was shorter（ P 〈 0. 001 ） in the Angioseal group （2.9 ± 0.7 hours） than in the control group （23.6 ± 6.2 hours）. There were no major complications in either group, and the incidences of minor complications and the rate of successful hemostasis were not significantly different. Conclusions The use of Angioseal arterial puncture dosing de vices is a safe, effective and simple method after coronary intervention to achieve immediate hemostasis.