无心房颤动的缺血性卒中患者抑郁状态与血管危险因素的关系

The Relationship Between Depression After Ischemic Stroke and Vascular Risk Factors

目的:探讨无心房颤动的缺血性卒中患者抑郁状态与血管危险因素之间的关系。方法:对59例无心房颤动的缺血性卒中患者随访12-18个月(平均13个月),采用24项Hamilton抑郁量表(HAMD)对患者进行评分,得分<8分为无抑郁症状,8-17分为抑郁状态,>17分为抑郁。收集患者单项血管危险因素、血管危险因素总数以及三项血管危险因素数目之和(高血压、心脏病及糖尿病),分析卒中后抑郁与血管危险因素的关系。结果:抑郁的发生与心脏病家族史、既往卒中史以及三项血管危险因素数目之和有关(P<0.05)。结论:无心房颤动的缺血性卒中患者卒中后抑郁的发生与血管危险因素有关,但相关性不强。

Objective： To determine the relationship between post-stroke depression （PSD） and vascular risk factors in a well-defined ischemic stroke cohort. Methods： 59 ischemic stroke patients with no atrial fibrillation were followed-up for about 13 months. The patients had been regularly tested by the Hamilton Depression Rating Scale for Depression（HAMD）. The patients were divided into three groups according to their scores of HAMD with cutoff point at 〈 7, 8-17, and 〉 17. The information about the vascular risk factors and the numbers of hypertension, heart disease and diabetes of the patients were also collected. Results： There were differences in the history of stroke, the family history of heart disease and the numbers of hypertension, heart disease and diabetes （P 〈 0.05） between depressive and non-depressive patients. Conclusion： Vascular risk factors were associated with PSD, but the link was weak.