脑胶质瘤术后立体定向放射治疗(SFR)疗效观察

The efficacy of stereotactic fractionation radiotherapy for postoperation remnant gliomas

目的回顾性分析脑胶质瘤术后多分割立体定向放射治疗(SFR)的疗效。方法16例脑胶质瘤术后患者,8例行常规放疗(RT)+立体定向放疗,8例单行立体定向放疗。肿瘤剂量(DT)(57.72±10.33)Gy。结果低分级脑胶质瘤(I、II级)1、2、3年生存率为100%(6/6)、100%(6/6)、83.3%(5/6),高分级脑胶质瘤(III、IV级)1、2、3年生存率为80%(8/10)、70%(7/10)、50%(5/10)。结论采用多分割立体定向放射治疗治疗脑胶质瘤有较好的临床疗效,是控制肿瘤生长及延迟复发的重要辅佐治疗手段。

Objective： A retrospective analysis was carried out to evaluate the results of gliomas treated by stereotactic fractionation radiotherapy. Methods：Sixteen evaluable gliomas patients were studied retrospectively , 8 patients with remnant gliomas after their operation received radiotherapy ＋ stereotactic fractionation radiotherapy, 8 patients with remnant gliomas after their operation received stereotactic fractionation radiotherapy, the irradiation was （x^- ±s ）57.72 ＋ 10.33GY. Results： The 1 - ,2 - ,and 3 -year survival rates of patients with low grade gliomas were 100%, 100%, 83.3%, 80% ,70% ,50% for those patients with high grade gliomas . Conclusion： Post - operation stereotactic fractionation radiotherapy is an important method to inhibit growth of tumor and the recurrence of tumor.