摘要
用双抗体夹心法（ＥＬＩＳＡ）检测了９６例中晚期胃癌、１７例早期胃癌和１６例胃溃疡患者血清ＬＮ和ｓＩＬ－２Ｒ水平。结果表明：中晚期胃癌患者血清ＬＮ含量明显高于健康对照组和胃溃疡患者，也高于早期胃癌患者，早期胃癌、中晚期胃癌患者血清ｓＩＬ－２Ｒ水平呈进行性增高。以健康人血清ＬＮ和ｓＩＬ－２Ｒ水平上限为界，中晚期胃癌ＬＮ阳性率为８７．５％，中晚期胃癌的ｓＩＬ－２Ｒ阳性率为８８．５％，早期胃癌阳性率分别为２９．４％和５２．９％。提示ＬＮ和ｓＩＬ－２Ｒ血清学检测可作为胃癌辅助诊断和病情监测的参考指标。
The serum laminin(LN)and slL-2R in 58 patients with advanced gastric cancerwere tested by ELISA method.The levels of both LN and sIL-2R were significantly increased incancer cases in comparison with healthy controls and with gastric ulcer patients(P<0.01).87. 5%and 88.5%of gastric canccr patients showed the increase of the values of LN and slL-2Rrespectively. The results indicated that the serum LN and slL-2R level may be helpful to thedifferential diagnosis and to the prognosis of gastric tumor.A higher level of both LN and slL-2R means bad prognoisis.
出处
《肿瘤研究与临床》
CAS
1996年第4期227-229,共3页
Cancer Research and Clinic
