深圳市肠道病毒71型血清流行病学初步调查

Serological Epidemiology Investigation of Enterovirus Type 71 Infection in Shenzhen

目的探讨深圳市不同人群肠道病毒71型血清流行病学规律。方法收集1999-2003年深圳地区正常人血清584份,按年龄0～岁、1～岁、2～岁、5～岁、15～岁和>30岁分成6个组,用ELISA方法对其肠道病毒71型抗体进行检测。结果1999-2003年深圳地区正常人血清中肠道病毒71型抗体阳性率最高的年龄组为5～岁组,阳性率超过50%;15～岁和>30岁组血清阳性率分别为47.7%和39.8%;2～岁血清阳性率约为30%,其中0～岁和1～岁两个低年龄组的血清阳性率最低,不超过20%。结论5岁以下低年龄儿童是肠道病毒71型的易感人群。

Objective To study serological epidemiology of EV71 infection in Shenzhen. Methods 584 healthy people of all age were tested for anti-EV71 antibody from 1999-2003 using ELISA. Results 35.4% of all samples were anti-EV71 positive. The seropositive rate for EV71 of the age group of 5- years old was the highest, 〉 50%; the rates of age groups 15- years old and 〉30 years old were 47.7% and 39.8%, respectively; the rates of age group 0- year old and 1- years old were the lowest, 〈 20%. Conclusion Children under five are susceptible to EV71 infection.