活体线索细胞分级法对细菌性阴道病的诊断价值

Applicaion of Living Clue Cell Grading in the Bacterial Vaginosis Diagnosis

【目的】探讨活体线索细胞分级法在诊断细茼性阴道痛（BV）中的应用价值。【方法】采用多功能超高倍显微镜分析仪（THMMDI-UP）查找线索细胞并计算其在上皮细胞中所占的百分比进行分级。【结果】BV病人与非BV病人中线索细胞为＋的比例两者相比较，差异无显著性（P〉0．05）；线索细胞为＋＋～＋＋＋＋所占比例两组相比较，差异有极显著性（P〈0．01），当线索细胞达到＋＋以上时，对BV诊断的敏感性为100％，特异性为95．5％。【结论】活体线索细胞分级可作为BV诊断的半定量指标，且操作简单，无需染色，优于传统的革兰染色分级法。

[ObjectivelTo study the value of Living clue cell grading in the diagnosis of bacterial vaginosis （BV）. [Methods]Five hundred BV patients were diagnosed by clinical symptoms and THMMDI-UP and graded according to the ratio of Biving clue cell in the epithelium with THMMDI-UP. [Results]There was no difference between patients with BV and without BV when the ratio of Living clue cell was epual to or over 20% and less than 40% （＋）（ P 〉0. 05）. There was however significant difference between them when the ratio of clue cell was above 40%（＋＋～＋＋＋＋）. When the ratio of Living clue cell was equal to or above 40% ,the sensitivity and specificity rates were 100 % and 95.5% respectively in the BV diagnosis. [Conclusion]Living Clue cell grading by THMMDI-UP could be considered as a semiquantitive index in the BV diagnosis. It is better than traditional Gram＇s stain with simpler operation.