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CAG方案治疗老年骨髓增生异常综合征RAEB和RAEB-T的近期疗效 被引量:5

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摘要 【目的】探讨CAG预激方案治疗老年骨髓增生异常综合征(MDS)难治性贫血伴原始细胞增多(RAEB)和难治性贫血伴原始细胞增多转变型(RAEB-T)的近期临床疗效。【方法】应用小剂量阿糖胞苷(Ara-C)、阿克拉霉素(Acla)、粒系集落刺激因子(G-CSF)组成的CAG预激方案治疗22例老年MDS-RAEB和MDS-RAEB-T,观察其疗效和不良反应。对照组予小剂量Ara-C治疗。【结果】22例患者中完全缓解10例,部分缓解6例,CR率45.5%,总有效率72.7%(16/22),明显高于对照组(27.8%,5/18)。毒副反应主要为骨髓抑制,但均不严重,非血液学不良反应少。【结论】CAG方案治疗老年MDS-RAEB和MDS-RAEB-T疗效肯定,不良反应少。
出处 《医学临床研究》 CAS 2007年第1期108-109,共2页 Journal of Clinical Research
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参考文献9

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