力月西芬太尼硬膜外给药用于术后镇痛的临床观察

Midzolam Combined with Fentayl ln Postopetative Patient——Controlled Epidural Analgesia

目的探讨力月西复合芬太尼硬膜外给药的镇痛效果。方法60例ASA I-Ⅱ级中下腹手术,硬膜外间隙均选择L1、2或T12L1,2%利多卡因术中维持麻醉,将上述病例随机分为两组;A组根据需要术中硬膜外腔给力月西0.15mg^0.20mg/kg,芬太尼0.05mg,术后硬膜外镇痛,0.10%布比卡因、6μg/ml芬太尼、0.133%力月西;B组根据需要术后硬膜外镇痛,0.10%布比卡因、6μg/mg芬太尼。主要观察术后12、24、36、48小时,VAS评分,用药总量。结果VAS评分B组(P<0.05),镇静评分A组>B组(P<0.05),药试物B组>A组(P<0.01)。结论力月西芬太尼复合麻药镇痛效果更为确切。

Objective To study the postoperative analgesia effect of Midaxolam ccombined Fentanyl given via patient - Controlled analgesia device during epeidural. Methods 60 sujects ASA Ⅰ-Ⅱ, were scheduled for mid - lower abdominal surgery. Epidural catherer was kept in the T12 L1 or L1-2. Durig the operation, 2% lidoaine was administer. The Patients were randomly divided into two groups. In group A, 0.10% bupicaine, 0. 133%midazolam, 6μg/ml fentanyl, Midazolam 0.15mg-0.20mg/ml were added through epidural in need. In group B, 0.1% bupicaine ＋ 6g/ml fentanyl, Midazolam 0.10-0.15% mg/kg was added though venous in need. The visual analog scale {VAS）seeation 12, 24, 36, 48h. Results VAS in group B was higher than that in goup A （P 〈 0. 015）. The sesstions in group A was higher than that in goup B（ P〈 0.05）. Conclusion Midazlam combined with fentayl is more effective for postoperative patient - controlled epidural analgesia.