消痤汤联合异维A酸胶丸治疗重症痤疮的临床观察

COMBINATION OF XIAOCUOTANG AND ISOTRETINOIN CAPSULES SEVERE ACNE

目的探讨重症痤疮的有效治疗方法。方法治疗组62例,采用自拟中药消痤汤联合异维A酸胶丸治疗;对照组47例,单用异维A酸胶丸治疗。4周为1疗程,治疗8周后评定疗效。结果治疗组基本治愈26例(占41.94%),显效24例(占38.71),有效9例(占14.51%),无效3例(占4.83%),总有效59例(占95.16%)。对照组基本治愈8例(占17.02%),显效16例(占34.04%),有效15例(占31.91%),无效8例(占17.02%),总有效39例(占82.97%)。两组基本治愈率和总有效率比较均有显著性差异(P<0.01,P<0.05)。结论中药消痤汤联合异维A酸胶丸治疗重症痤疮比单独应用异维A酸胶丸的疗效好,副作用少,值得推广应用。

Objective To explore the therapy of severe acne. Methods 62 cases in the treatment group were treated with the self developed Xiaocuotang, atraditional Chinese medicine, and isotretinoin capsules while 47 case in the contrast group were treated with isotretinoin capsules, 4 weeks as a course of treatment in both group. Curatire effects were evaluated 8 weeks later. Results The total effective rate in the treatment group was 95.16% （59 cases）, and among them, 26 cases （41.94%） were cured, 24 （38.71% ） got much improved 9 （14.51%） got some effects and 3（4.83%） no effects. The total effective effect in the contrast group was 82.97% （39 cases ） ,and among them 8 cases（17.02% ） were cured, 16（34.04% ） got much improved, 15（31. 91% ） got some effects and 8 （17.02 % ） no effects. There existed significant differences in the curative effects and the total effective rates between the two groups（ P 〈 0.01; P 〈 0.05）. Conclusion The combined use of xiaocuotang and isotretinoin capsules can produce good curative effects with few side effects.