肝切除术治疗原发性肝癌破裂出血26例分析

Hepatectomy for Spontaneous Rupture and Hemorrhage of Primary Liver Cancer(A Report of 26 Cases)

目的探讨肝切除术治疗原发性肝癌破裂出血的疗效。方法回顾性分析我院1998年1月-2003年12月肝切除术治疗原发性肝癌破裂出血26例患者，以同期行肝切除术的26例非破裂肝癌病例作为对照，比较两组病例的各项临床资料及预后。结果破裂组术中出血量（1306．3±603．2）ml、输血量（790．7±480．1）ml，较非破裂组的（711．2±330．7）ml与（450．1±288．3）ml显著为高（P〈0．05）；破裂组术后1年生存率为57．7％，低于非破裂组的84．6％（P〈0．05），但3年生存率为26．9％，与非破裂组（30．8％）相近（P〉0．05）。结论肝切除术治疗原发性肝癌破裂出血效果确切，应尽量施行。

Objective To study the effect of hepatectomy for spontaneous rupture and hemorrhage of primary liver cancer （PLC）. Method 26 cases of hepatectomy for spontaneous rupture and hemorrhage of PLC（ group A） admitted from January 1998 to December 2003 were reviewed with a comparative analysis to 26 cases of routine hepatectomy （group B） during the same period. Result The intraoperative blood loss was （1306.3 ± 603.2）ml and the transfusion volume was （790.7 ± 480.1 ）ml in group A, which were significantly higher than the group B of （ 711.2 ± 330.7 ） ml and （450.1 ± 288.3 ） ml. The 1 -year survival rate in group A was significantly lower than group B （57.7% vs. 84.6% , P 〈 0. 05 ）. But the 3-year survival rates was similar （26.9% vs. 30.8%, P 〉 0. 05 ）. Conclusions The hepatectomy for the spontaneously ruptured of PLC patients is indicative.