中老年人体成分与骨密度的相关性研究

Gender Differences in Relationship between Body Composition Components and Bone Mineral Density in Middle-aged and Aged Person

目的:研究中国天津地区中老年男性和女性骨密度(BMD)与年龄、BMI、脂肪量(FM)、非脂肪量(FFM)、腹部脂肪含量(ABDFM)的关系。方法:选择中老年男性82例,用双能X线吸收测量法(DXA)测量腰椎2￣4(L2￣4)BMD、全身BMD和体成分,并与中老年女性106例做对照比较。结果:(1)FM、FFM、ABDFM、BMI与中老年男性和女性BMD均呈显著正相关,年龄与BMD呈负相关;(2)多元线性回归分析显示,FFM是影响中老年男性BMD变化的主要决定因素;而FM是影响中老年女性BMD变化的主要决定因素;ABDFM可能影响中老年女性的L2￣4BMD。结论:中老年人的FM、FFM均与BMD呈正相关,并且具有性别差异;ABDFM与BMD有关,故腹型肥胖可能对L2￣4BMD有保护作用。

Objective： To investigate the relationship between bone mineral density （BMD） and age, body mass index （BMI）, fat mass （FM）, fat-free mass （FFM）, abdominal fat mass（ABD FM） in middle-aged and aged men and women in Tianjin area of China. Methods：BMD at lumber spine2-4 CL2-4）,total （TOT） bone and body composition were measured by dual energy X-ray absorptiometry （DXA） in eighty-two middle-aged and aged men and compared with one hundred and six middle-aged and aged women who were controlled. Results： （1）FM, FFM,ABD FM and BMI were all positively correlated with BMD, age was negatively correlated with BMD in middle-aged and aged men and women. （2）Muhiple regression analysis revealed that FFM was a main determinant of BMD in men while FM was a main determinant of BMD in women and ABD FM might influence on L2-4 BMD in senior woman. Conclusion： FM and FFM are positively correlated with BMD and there are gender differences in the middle-aged and aged persons. Abdominal obesity is related with BMD and has protective effects on lumber spine L22-4 BMD.