肾囊肿乙酸注射硬化治疗的临床应用

Clinical study of CT-guided sclerotherapy using 50 percent acetic acid in the treatment of renal cyst

目的探讨乙酸作为肾囊肿硬化剂的作用,比较乙酸和无水乙醇硬化治疗的效果。方法应用螺旋CT引导,对85例肾囊肿患者进行硬化治疗,其中43例采用无水乙醇作为硬化剂,42例采用50％乙酸作为硬化剂。所有患者抽净囊液后,注入硬化剂留置一定时间,然后将硬化剂抽出。结果无水乙醇组中囊腔的消失率为55．8％(24／43),50％乙酸组的囊腔消失率为71．4％(30／42)。无水乙醇组并发症的发生率为16．3％(7／43),50％乙酸组的发生率为4．8％(2／42)。无水乙醇组硬化剂囊腔内的保留时间为(20±4)min,50％乙酸组的保留时间为(10±2)min。两组间差异有非常显著意义(P<0．01)。结论5 0％乙酸作为硬化剂对肾囊肿进行硬化治疗,硬化效果好、不良反应小,可替代传统的无水乙醇硬化剂。

Objective To investigate the efficacy of 50% acetic acid as a renal cyst sclerotherapy agent, and with further comparison to that of absolute alcohol. Methods Eighty five patients with renal cyst were undergone sclerotherapy through spiral CT guidance including 43 cases with absolute alcohol and the others with 50% acetic acid as sclerosing agents. All the cysts were aspirated under CT-guidance, befo,ehand. The sclerosising agents were withdrawn from the cysts after a definite period of retention. Results The disappearance rates of cyst cavity with absolute alcohol and acetic acid were 55.81% and 71.42%, respectively. Complication occurence rates with absolute alcohol and acetic acid were 16.28% and 4.76%, respectively. The ave,age retention periods of absolute alcohol and acetic acid in cyst were （20 ± 4）minutes, and （10±2）minutes, respectively. Statistical analysis demonstrated that all the data in two groups were significantly different. Conclusion Using 50% acetic acid as sclerosising agent in treating renal cyst possesses the better effect and less side effect, providing a tendency to replace the traditional therapy.