期刊文献+

雌激素补充治疗在体外受精-胚胎移植中的应用研究 被引量:5

下载PDF
导出
摘要 人类辅助生殖技术(ART)已有很大的发展,虽然成功率有较大提高,但仍未达到预期水平。与正常育龄妇女相比,不孕患者经过降调和超促排卵治疗后,体内的激素水平会发生一系列的变化,这些变化影响生殖系统的内环境,特别是子宫内膜对胚胎的容受性,因此,有研究表明患者补充适当的激素可能提高内膜对胚胎的容受性,进而提高妊娠率。目前,不孕患者黄体期需补充孕酮已被广泛接受,但是否应该补充雌激素即雌激素补充治疗仍存在争议,有待进一步研究证实。
作者 易姣 刘雨生
基金 安徽省卫生厅重点学科科技进步专项资助(编号:2004Z008)
  • 相关文献

参考文献20

  • 1Abate A, Brigandi A, Costabile L, et al. 17-alpha-hydroxyprogeryerone caproate and natural progesterone in assisted reproduction: a comparative study[J]. Clin Exp Obstet Gynecol, 1997,24(4):190-192.
  • 2Ghosh D, Sengupta J. Another Look at the tissue of Preimplantation oestrogen[J]. Hum Reprod, 1995,10( 10):1-2.
  • 3Sharara FI, McClamrock HD. Ratio of oestradiol concentration on the day of human chorionic gonadotrophin administration to mid-luteal oestradiol concentration is predictive of in-vitro fertilization outcome [J]. Hum Reprod, 1999, 14 (11) : 2777- 2782.
  • 4Baird DD, Wilcox AJ, Weinberg CR, et al. Preimplantation hormonal differences between the conception and non-conception menstrual cycles of 32 normal women [ J ]. Hum Reprod, 1997,12 ( 12 ) :2607-2613.
  • 5Pritts EA, Atwood AK. Luteal phase support in infertility treatment a meta-analysis of the randomized trials [J]. Hum Reprod, 2002 , 17 (9) : 2287-2299.
  • 6Vicdan K, Zeki Isik A. Luteal phase hormonal profile in prediction of pregnancy outcome after assisted reproduction [J]. Eur J Obstet Gynecol Reprod Biol, 2001 , 96 ( 1 ) : 98-101.
  • 7Chen CH, Zhang X, Barnes R, et al. Relationship between peak serum estradiol levels and treatment outcome in in vitro fertilization cycles after embryo transfer on day 3 or day 5 [J]. Fertil Steril, 2003,80(1) :75-79.
  • 8Hung Yu Ng E, Shu Biu Yeung W, Yee Lan Lau E, et al. A rapid decline in serum oestradiol concentrations around the midluteal phase had no adverse effect on outcome in 763 assisted reproduction cycles[J]. Hum Reprod, 2000,15(9) : 1903-1908.
  • 9Friedler S, Zimerm A, Schachter M, et al. The midluteal decline in serum estradiol levels is drastic but not deleterious for implantation after in vitro fertilization and embryo transfer in patients with normal or high responses [J]. Fertil Steril, 2005, 83 (1):54-60.
  • 10Valbuena D, Jasper M, Remohi J, et al. Ovarian stimulation and endometrial receptivity [ J ]. Hum Reprod, 1999,14 [ Suppl 2 ] : 107-111.

同被引文献46

引证文献5

二级引证文献26

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部