慢性阻塞性肺疾病患者的能量代谢与人体成分

The energy metabolism and body composition in chronic obstructive pulmonary disease patients

慢性阻塞性肺疾病（COPD）主要累及肺，但也可引起显著的全身效应，主要表现为全身性炎症反应和骨骼肌萎缩。本文主要综合了近年来国外有关COPD患者的能量代谢和人体成分的变化及其可能的机制方面的最新研究结果，同时对COPD营养干预的临床试验研究结果进行了总结，提出今后进一步探讨COPD患者营养不良发生机制和营养干预治疗的研究方向。

Chronic obstructive pulmonary disease（COPD） affects the lungs, but it also produces significant systemic effects, including systemic inflammation and skeletal muscle wasting. This article reviewed the latest advances in the energy metabolism and body composition in COPD patients, summarized the results of some clinical trials of nutritional intervention in COPD patients and proposed the study direction for further investigation of the mechanisms of malnutrition and nutritional therapy in COPD.