利多卡因丙泊酚和瑞芬太尼全凭静脉复合麻醉的观察

Effects of Comb-Lidocaine on the Dosages of Propofol and Remifentanil in total intravenous anesthesia.

目的：探讨利多卡因在复合静脉麻醉中的作用，以及对异丙酚、瑞芬太尼的影响。方法：60例鼓室成形手术的病人按时间顺序分为两组，丙泊酚、瑞芬太尼复合利多卡因（RL）组，对照组不复合利多卡因（R）。观察利多卡因复合麻醉时异丙酚、瑞芬太尼的用量，复苏时自主呼吸恢复时间及呼醒时间。结果：复合利多卡因能降低丙泊酚、瑞芬太尼的用量，与对照组有显着差异（P〈0．05）；自主呼吸、唤醒时间不延长（P〉0．05）．结论：利多卡因复合麻醉能降低异内酚、瑞芬太尼的用量，且心率稳定，不影响麻醉苏醒。

Objective To study the effect of comb--Lidocaine on the dosage of Propofol and Remifentanil in total intravenous anesthesia（TIVA）. Method Sixty patients with tympanic cavity plastic operation were assigned to two groups by time, Remifentanil with lidoeaine group （RL） and simple Remifentanil group（R）. Dosage of Propofol and Remifentanil, resuming time of the spontaneous breathing and awakening time in recovery period were observed. Results Compared with control group, comb-Lidocaine in TIVA could decreased the dosage of Propofol and Remifentanil （ P 〈 0. 05）, the resuming time of spontaneous breathing and the awakening time were no effect（ P〉0.05）. Conclusion Comb-Lidocaine in TIVA can decrease the dosages of Propofol and Remifentanil, the heart rate may keep stable and the time of recovery period have no effect.