摘要
目的:调查药物不良反应(ADR)发生情况,促进临床合理用药。方法:对本院门诊留察室上报的172例ADR报告分别从患儿年龄、性别、涉及药物种类及临床表现、联合用药情况等方面进行分析和统计。结果:172例ADR报告中涉及药品36种,β-内酰胺类抗生素占56.98%,抗感染中药占26.74%,临床表现以皮肤过敏反应最多占64.53%。结论:应重视ADR监测工作,促进临床合理用药。
Objective:To study the characteristics of adverse drug reaction(ADR) in our hospital and to promote a rational clinical use of drugs. Methods: 172 ADR cases had been collected from observation room of out-patient department in our hospital. All cases were analyzed in respects of age, sex, drugs administrated, clinical manifestation and drug combination etc. Results: 36 kinds of drugs causing ADR were reported in these 172 cases, with β-lactam antibiotics accounting for 56.98% and anti-infection traditional Chinese medicine accounting for 26.74%. Most were induced by skin anaphylaxis, which accounted for 64.53%. Conclusions: ADR monitor must be strengthened in order to guide the clinically rational use of drugs.
出处
《儿科药学杂志》
CAS
2007年第1期23-25,共3页
Journal of Pediatric Pharmacy
关键词
门诊
留查患儿
药物不良反应
Out-patient department
Under-observation children
Adverse drug reaction