脑出血大鼠模型的血液流变学研究

Hemorheology Study of Brain Hemorrhage Rat Model

目的:观察自体血注射法造成大鼠脑出血(ICH)的血液流变学的变化。方法:采用自体尾静脉血注入法诱导大鼠脑出血模型,将60只SPF级SD大鼠随机分为空白组、模型组,分别对各组大鼠血液采用LBY-N6A血流变测试仪检测。结果:模型组与空白组比较有显著性差异(P<0.05)。结论:自体血注射法造成大鼠脑出血模型,通过空白组和模型组对血液流变学的比较,证明造模方法的可靠性。

Objective： To study on blood rheology of intracerebral hemorrhage rats with autoblood injection method. Methods： Brain hemorrhage rnodel rats were established by autoblood injection method. 60 rats were randomly divided into blank group and model group. Rattish blood was detected by LBY- N6A test instrument. Results： There was significant deviation between model group and blank group （P〈0.05）. Conclusion： It was proved that autoblood injection method was reliable.