我院2005年244例药品不良反应报告分析

Analysis of 244 ADR Cases in Beijing Tongren Hospital in 2005

目的了解我院药品不良反应(ADR)发生的特点及规律。方法对我院2005年收集到的244例ADR报告进行回顾性分析。结果244例ADR中,女性多于男性;≥40a者占79.83%;心血管系统药引起的ADR最为多见,占45.69%,其次为抗微生物药;以静脉给药方式引发的ADR为主;ADR发生频率最高的为前列地尔注射液(凯时),占9.02%;皮肤及其附件损害最多,占28.14%。结论应重视ADR的监测和ADR知识的宣传,强化医务人员对ADR严重性和危害性的认识。

OBJECTIVE：To investigate the characteristics of adverse drug reactions（ADR） in our hospital so as to promote rational clinical drug use.METHODS： 244 ADR cases collected in 2005 in our hospital were analyzed retrospectively.RESULTS：Among the 244 cases, the female exceeded the male;79.83% of the patients were more than 40 years old.The cardiovascular system medicines took the lead which amounted to 45.69% of the total, then came the antimicrobial medicines. The intravenous administration caused most of ADRs.Alprostadil Injection accounted for 9.02% of the total, the highest.Skin and its appendages impairment cases took the biggest percentage at 28.14% .CONCLUSION：we should pay more attention to the ADR monitoring and the spread of ADR knowledge and enhance the ADR awareness of medical staff.sen or avoid the occurrence of ADR,monitoring of which and publicizing of ADR knowledge should be emphasized.