期刊文献+

胰腺癌免疫治疗进展 被引量:3

Research advancement on the immunotherapy of pancreatic cancer
原文传递
导出
摘要 随着分子生物学技术和肿瘤免疫学的发展,免疫治疗已成为肿瘤综合治疗模式的重要组成部分。近年来胰腺癌免疫治疗的研究也日趋增多,可望为胰腺癌的治疗开辟新的途径。现综述胰腺癌特异性主动免疫治疗、单克隆抗体治疗、细胞因子治疗和过继性细胞免疫治疗等进展。 Along with the advancement in molecular biotechnology and tumor immunology,the immunotherapy has been an important part in the mode of combined therapy of tumour. The researches on the immunotherapy of pancreatic cancer become more and more in recent years ,they may give a new way to treat pancreatic cancer. This article reviews the immunotherapy of pancreatic cancer in aspects such as specific active immunotherapy, monoclonal antibody therapy, cytokine therapy and adoptive cellular immunotherapy.
出处 《国际肿瘤学杂志》 CAS 2007年第1期58-61,共4页 Journal of International Oncology
关键词 胰腺肿瘤 免疫疗法 生物疗法 Pancreatic neoplasms Immunotherapy Biological therapy
  • 相关文献

参考文献24

  • 1Rosenberg L.Pancreatic cancer:a review of emerging therapies.Drugs,2000,59 (5):1071-1089.
  • 2Miyazaki J,Tsuzuki Y,Matsuzaki K,et al.Combination therapy with tumor-lysate pulsed dendritic cells and antiangiogenic drug TNP-470for mouse pancreatic cancer.Int J Cancer,2005,117 (3):499-505.
  • 3Morse MA,Nair SK,Boczkowski D,et al.The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer.Iht J Gastrointest Cancer,2002,32 (1):1-6.
  • 4Kalady MF,Onaitis MW,Emani S,et al.Dendritic cells pulsed with pancreatic cancer total tumor RNA generate specific antipancreatic cancer T cells.J Gastrointest Surg,2004,8 (2):175-181.
  • 5Gjertsen MK,Buanes T,Rosseland AR,et al.Intradermal ras peptide vaccination with granulocyte-macrophage colony-stimulating factor as adjuvant:Clinical and immunological responses in patients with pancreatic adenocarcinoma.Int J Cancer,2001,92(3):441-450.
  • 6Ramanathan RK,Lee KM,McKolanis J,et al.Phase I study of a MUC Ⅰ vaccine composed of different doses of MUC1 peptide with SB-AS2adjuvant in resected and locally advanced pancreatic cancer.Cancer Immunol Immunother,2005,54 (3):254-264.
  • 7Gilliam AD,Topuzov EG,Garin AM,et al.Randomised double blind placebo controlled multi-centre group sequential trial of G17DT for patients with advanced pancreatic cancer unsuitable or unwilling to take chemotherapy.J Clin Oncol,2004,22(14S):2511.
  • 8Takhar AS,Gilliam AD,Watson SA,et al.The effect of jaundice on the generation of anti-gastrin antibodies in G17DT immunized patients with advanced pancreatic cancer.Eur J Surg Oncol,2006,32 (2):197-200.
  • 9Wobser M,Keikavoussi P,Kunzmann V,et al.Complete remission of liver metastasis of pancreatic cancer under vaccination with a HLA-A2restricted peptide derived from the universal tumor antigen survivin.Cancer Immunol Immunother,2006,55 (10):1294-1298.
  • 10Gaudernack G,Buanes T,Meo M,et al.Clinical trials of a peptide based vaccine targeting telomerase.Proc Am Soc Clin Oncol,2003,22:166.(Abstr 666)

同被引文献46

引证文献3

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部