血液骨源性碱性磷酸酶的测定及临床应用

Blood Bone Alkaline Phosphatase (BAP) and the Clinic Importance of Mensuration

目的检测小儿/成人血中骨源性碱性磷酸酶(BAP)活性,籍以筛查或辅助诊断因钙营养不良引起的骨钙化障碍或其他原因引起的代谢性骨病。方法BAP活性测定采用免疫渗透和全血干化学技术原理研制而成,通过与标准比色板对照判读结果。结果通过儿童873人的NBAP检测,均值:(225±30)U/L;成人330例ABAP检测,均值(140±20)U/L。结论BAP的测定对辅助诊断因钙营养不良引起的骨钙化障碍或其他原因引起的代谢性骨病,对儿童和孕产妇科学补钙有较大的指导作用。

Object To detect the activity of bone alkali phosphatase （BAP） in child/aduh blood, to screen metabolic bone disease and bone calcification dysfunction for other reasons. Method BAP active detection passes with immunity infiltration and completely blood dry chemical technical principle R＆D with standard colorimetric board compare to sentence read result. Result NBAP were detected in 873 children： the mean value was 225 ±30 U/L; 330 adults ABAP were detected, the mean value was 140 ±20 U/L. Conclusion Detection of BAP was useful for assisting the bone calcification dysfunction or calcium malnutrition, or for supplying calcium scientifically for children and pregnancy lying-in woman.