术中输血量与肝癌术后肺部并发症的关系

Correlation between intraoperative massive blood transfusion and postoperative pulmonary complications after operation of liver cancer

目的探讨肝癌手术患者发生术后肺部并发症(PPC)与术中大量输血的关系。方法对230例因肝癌住院并接受剖腹手术治疗的病例资料进行回顾性分析,按术中输血量分为1000ml以下、1000～2000ml(含1000ml、2000ml)、2000ml以上3层,采用t检验的方法研究肝癌手术后发生肺部并发症(PPC)与术中输血的关系。结果术中输血量<1000ml、1000～2000ml、>2000ml三层患者中,PPC组输血制品总量及输注红细胞、血浆的量均显著高于非PPC组。结论术中输血量与肝癌患者术后肺部并发症的发生率呈明显的正相关关系。

Objective To investigate the relationship between intraoperative massive blood transfusion and postoperative pulmonary complications following operation of liver cancer. Methods From October 2000 to October 2004, clinical data of 230 patients undergoing operation of liver cancer were analyzed retrospectively. The patients were divided into three groups ： 〈1000 ml, 1000 ml-2000 ml, 〉2000 ml according to the total volume of intraopertive blood transfusion. The relationship between the postoperative pulmonary compliacations and intraoperative blood transfusion were studied by T test after operation of liver cancer. Results In the three groups, the volume of blood products transfusion, the volume of erythrocyte transfusion and the volme of plasma transfusion of group PPC were obviously higher than that volume of group Non-PPC during operation. Conclusion The volume of intraoperative blood transfusion has a positive correction with the incidence of PPC after operation of liver cancer.