摘要
建立了HPLC法测定依托泊苷微乳的含量。采用C18柱,流动相为甲醇-水(70∶30),检测波长285nm。依托泊苷在5~100μg/ml范围内线性关系良好。平均回收率为99.8%,RSD为1.3%。
A HPLC method was established for the determination of etoposide microemulsion. A C18 column was used with the mobile phase of methanol-water (70 : 30), at the detection wavelength of 285nm. The calibration curve was linear in the range of 5-100μg/ml. The average recovery was 99.8 % with RSD of 1.3 % (n=9).
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2007年第2期121-122,共2页
Chinese Journal of Pharmaceuticals