影响脑梗死患者预后的相关因素分析及血尿酸检测的意义

The Analysis of Prognostic Related Factor in Cerebral Infarction Patients and the Significance of Serum Uric Acid Detection

目的探讨影响急性脑梗死患者近期预后的相关因素及血尿酸检测的意义。方法分析86例急性脑梗死患者临床资料及血尿酸含量。结果未愈组与康复组比较,有高血压病史者比例和Cr、UA、ApoA1水平较高(P<0.05),而有吸烟、心肌梗死史、卒中史者比例及GLU、TC、TG、LDL、HDL、ApoB的水平无统计学意义(P>0.05)。Logistic回归分析筛选出三个主要影响因素:高血压病史、UA水平和ApoA1水平。血尿酸水平与脑梗死患者的预后相关,血尿酸水平高者,病情重,预后差(P<0.001)。结论脑梗死预后与高血压病史、血尿酸等危险因素有关,测定血尿酸含量有助于判断病情及评估近期预后。

Objective To investigate the prognostic related factor in acute cerebral infarction patients and the significance of serum uric acid detection. Methods To analyse the clinical data and the content of serum uric acid in 86 patients with acute cerebral infarction. Results Compared to restoration group, the proportions of patients with hypertension record and the level of Cr, UA and ApaA1 were higher in non-restoration group （ P 〈 0.05）. The proportions of patients with smoking, myocardial infarction, apoplexy and the level of GLU, TC, TG, LDL, HDL, ApoB were not statistically significant between two groups （ P 〉 0.05）. Three main impact factors were screened by Logistic regression analysis,which are hypertension record, the content of UA and the level of ApoA1 .The content of serum uric acid was correlated with the prognosis of cerebral infarction patients. The patients with higher serum uric acid concentration had bad prognosis（ P 〈 0.001 ）. Conclusion The prognosis of cerebral infarction was correlated with same risk factors, such as hypertension record and serum uric acid level, The determination of serum uric acid content was conduced to the estimate of pathologic condition and the evaluation of prognosis.