摘要
目的:探讨电针的不同波形对晚孕大鼠血清雌二醇(E2)、孕酮(P)含量及其比值的影响。取成年Wistar雌性大鼠50只随机分为5组,即正常对照组、妊娠对照组、连续波组、疏密波组、簇形波组。除正常对照组外均用直接造模法造成大鼠妊娠模型。19天后暴露腹腔,自腹主动脉采血,各电针组于针刺后60min后采血。测定血清雌二醇(E2)、孕酮(P)含量,并计算血清E2/P比值。结果:血清E2含量:连续波组极显著高于正常组、妊娠对照组(P<0.01);簇形波组极显著高于正常组、妊娠对照组(P<0.01);血清P含量:簇形波组显著高于正常对照组(P<0.05),极显著高于连续波组(P<0.01);血清E2/P含量:连续波组极显著高于正常对照组、妊娠对照组(P<0.01),极显著高于簇形波组、疏密波组(P<0.01);簇形波组显著高于正常对照组(P<0.05)。提示:连续波能最佳发挥合谷、三阴交二穴在内分泌及神经反射两方面地促分娩机制。
Objective: to explore the influences of different waveshapes with electro - acupuncture on the content and the ratio of blood -serum estradiol (E2 ) and progesterone (P) in delayed - pregnant rats. Methods: 50 adult female Wistar rats were randomly divided into 5 groups, including normal, controlled group, pregnant controlled group, continuous wave group, loose - dense wave group, clustershape wave group. All rats were made into pregnant model directly except normal controlled group. 19days later blood was taken from abdominal aorta (rats in electro - acupuncture groups were taken blood after 60mins'acupuncture). The content of blood - serum estradiol (E2 ) and progesterone (P) were determined and the ratio of E2 and P was calculated. Results: Content of blood - serum E2 in rats of continuous wave group was extremely significantly higher than that in normal controlled group and pregnant controlled group ( P 〈 0.01). Content of blood -serum E2 in rats of dustershape wave group was extremely significantly higher than that in normal controlled group and pregnant controlled group ( P 〈 0.01 ). Content of blood - serum P in rats of clustershape group was significantly higher than that in normal controlled group ( P 〈 0.05 ), and extremely significantly higher than that in continuous wave group ( P 〈 0.01 ). Ratio of E2 and P in rats of continuous wave group was extremely significantly higher than that in normal controlled group and pregnant controlled group ( P 〈 0.01 ), and extremely significantly higher than that in loose-dense wave group, clustershape wave group ( P 〈0.01 ). Ratio Of E2 and P in rats of clnstershape group was significantly higher than in normal controlled group ( P 〈 0.05 ). Conclusion : Continuous wave in Hegu and Sanyinjiao points can best induce parturition in endocrine and nervous reflex aspect.
出处
《中华中医药学刊》
CAS
2007年第2期388-389,共2页
Chinese Archives of Traditional Chinese Medicine
关键词
电针
波形
晚孕
雌二醇
孕酮
electro - acupuncture
waveshapes
delayed - pregnant
estradiol ( E2 )
progesterone (P)