下颌骨溶骨症1例报告及文献复习

Gorham's disease in the mandible: Report of one case and review of the literature

溶骨症又称Gorham综合征,临床罕见,其病因及发病机制尚不清楚,以自发性进行性骨溶解吸收为主要临床表现。溶骨症可发生于任何年龄,特别好发于5～25岁,无明显性别差异。可发生于单一骨骼,也可跨过关节,侵犯多个骨骼。目前认为,早期彻底切除可有效阻止病变进展。作者报告1例,并结合相关文献,对该病的临床特点、好发部位、诊断与鉴别诊断及治疗方法进行讨论。

Gorham＇s disease is an extremely rare condition with fewer than 200 cases reported in the medical literature. It is described as gradual and often complete spontaneous resorption of bone tissue. Now the primary mechanism of the disease is unknown. and the disease is most often seen in children and young adults of either gender, and mainly affects bones that develop by intramembranous ossification. The case presented involves a 51-year-old man with Gorham＇s disease in the mandible. The clinical features associated with Gorham＇s disease were discussed, and diagnosis, pathogenesis and treatment were summarized.