期刊文献+

胃肠间质瘤诊断和治疗进展 被引量:25

原文传递
导出
摘要 胃肠间质瘤(gastrointestinal stromaltumor,GIST)是最常见的胃肠道间叶组织来源的肿瘤。好发于胃和小肠。男性略高于女性.发病年龄6d至93岁。中位年龄55~65岁,高峰年龄60岁。可发生于消化道的任何部位,最常见的原发部位是胃(65%~70%)和小肠(25%~30%),其次为结直肠(5%~10%)和食管(5%),还可以发生于网膜、系膜和后腹膜等胃肠外部位 。
出处 《中华胃肠外科杂志》 CAS 2007年第1期91-94,共4页 Chinese Journal of Gastrointestinal Surgery
  • 相关文献

参考文献3

二级参考文献42

  • 1贺慧颖,项一宁,李燕,钟镐镐,吴秉铨,郑杰.胃肠道间质瘤60例中c-kit和PDGFRA基因突变的检测[J].北京大学学报(医学版),2005,37(3):320-324. 被引量:10
  • 2Miettinen M, Majidi M, Lasota J. Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs) : a review. Eur J Cancer,2002, 38 : S39 -S51.
  • 3Joensuu H, Kindblom LG. Gastrointestinal stromal tumors-a review.Acta Orthop Stand Suppl, 2004, 75:62-71.
  • 4Heinrich MC, Corless CL, Duensing A, et al. PDGFRA activating mutations in gastrointestinal stromal tumors. Science, 2003, 299:708 -710.
  • 5Corless CL, Schroeder A, Griffith D, et al. PDGFRA mutations in gastrointestinal stromal tumors: frequency,, spectrum and in vitro sensitivity to imatinib. J Clin Oncol, 2005, 23:5357-5364.
  • 6Debiec-Rychter M, Dumez H, Judson I, et al. Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase Ⅰ and Ⅱ studies of the EORTC Soft Tissue and Bone Sarcoma Group. Eur J Cancer 2004,40:689-695.
  • 7Noma K, Naomoto Y, Gunduz M, et al. Effects of imatinib vary with the types of KIT-mutation in gastrointestinal stromal tumor cell lines.Oncol Rep, 2005, 14:645-650.
  • 8Fletcher CD, Berman JJ, Corless C, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol,2002, 33:459-465.
  • 9Lasota J, Jasinski M, Satlomo-Rikala M, et al. Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomas. Am J Pathol, 1999, 154:53-60.
  • 10Kim TW, Lee H, Kang YK, et al. Prognostic significance of c-kit mutation in localized gastrointestinal stromal tumors. Clin Cancer Res, 2004, 10:3076-3081.

共引文献167

同被引文献172

引证文献25

二级引证文献82

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部