类固醇性青光眼临床分析

A Clinical Analysis on 24 Cases with Glucocorticoid Induced Glaucoma

目的探讨类固醇性青光眼的病因、临床特点及预防治疗。方法对24例(41眼)类固醇性青眼资料进行分析。结果局部应用类固醇17例(70.8%),全身用类固醇7例(29.2%)。13眼停用类固醇后压得到控制;20眼给予局部和全身使用抗青光眼药物治疗后眼压得到控制;8眼眼压未得到控制者行手术疗。结论滥用类固醇药物是发生类固醇性青光眼的重要原因,应合理应用类固醇激素,避免医源性青光眼发生。(中国眼耳鼻喉科杂志,2007,7:37～38)

Purpose To investigate the etiology, clinical characteristics, prevention and treatment of glucocorticoid induced glaucoma （GIG）. Methods The data of 24 cases （41 eyes） with glucocorticoid induced glaucoma were retrospectively analyzed. Results Seventeen patients had history of using glucocorticoid locally （70. 8% ）, 7 cases, systemically（29.2% ）. The introocular pressure （IOP） of 13 eyes was controlled after stopping glucocorticoid administration; The lOP of 20 eyes was controlled by using antiglaucoma drug locally or systematically. The lOP of the rest of 8 eyes were not controlled satisfactorily and surgery was required. Conclusion Elevated lOP after long term use of glucocorticoid is common. Abuse of glucocorticoid is a leading cause for glaucoma. It is important that this kind of steroid should be used appropriately for reducing the risk of iatrogenic ophthalmocace. （Chin J Ophthalmol and Otorhinolaryngol, 2007,7：37-38）