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糖尿病性微血管病的临床病理生理 被引量:12

Clinical pathophysiology of diabetic microangiopathy
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摘要 In present review,the history of microangiopathy discovery and it’s modern concept were introduced and the pathophysiological changes of some vital organs in diabetes were analyzed.The roles of oxidation stress,distur-bances of microvascular functions,microvascular endothelial cell damage,PKC and PPARγ in pathogenesis of diabetic microangiopathy were also discussed. In present review, the history of microangiopathy discovery and it's modem concept were introduced and the pathophysiolagical changes of some vital organs in diabetes were analyzed. The roles of oxidation stress, disturbances of microvascular functions, microvascular endothelial cell damage, PKC and PPARγ in pathogenesis of diabetic microangiopathy were also discussed.
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2007年第2期399-402,共4页 Chinese Journal of Pathophysiology
基金 国家自然科学基金重点项目(No.30230380) 上海市科委重大课题资助(No.04dz19504)
关键词 微血管病 氧化性应激 蛋白激酶C 过氧化酶体激增剂活化受体-γ Microangiopathy Oxidative stress Protein kinase C Peroxisome proliferator -activated receptor γ
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参考文献27

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二级参考文献16

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